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InChi: InChI=1S/C22H30N4O3S/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16(27)11-26(17)21(29)19(23)22(2
and attenuates tau hyperphosphorylation and neurofibrillary tangles (NFT) formation via promoting protein phosphatase 2A (PP2A) activity
325715-02-4
It first became available in Europe in 1984
SKF-96365 hydrochloride Size:2mg solid InChi: InChI=1S/C22H30N4O3S/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16(27)11-26(17)21(29)19(23)22(2SKF 96365 hydrochloride is a potent TRP channel blocker and a store operated Ca2+ entry (SOCE) inhibitor. SKF 96365 hydrochloride significantly inhibits hERG, hKCNQ1 hKCNE1, hKir2. 1 and hKv4. 3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF 96365 hydrochloride exhibits potent anti neoplastic activity by inducing cell cycle arrest and apoptosis in colorectal cancer cells. Product information CAS Number: 130495