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Navoximod (GDC-0919
Formula: C21H17Cl2F2N3O2
InChiKey: UPJKMGHIPNYNEY-UHFFFAOYSA-N
pneumoniae strain and VIM-2 of P
Plecanatide A3-IN-2 Navoximod (GDC-0919Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase C (GC C) receptor agonist. Plecanatide activates GC C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti inflammatory activity in models of murine colitis. Product information CAS Number: 467426 54 6 Molecular Weight: 1681. 89 Formula: C65H104N18O26S4 Chemical Name: (4S) 4 [(2S) 2 [(2S) 2 amino 3 carbamoylpropanamido] 3