Isosilybin A - CAS# 142796-21-2 inib Hydrochloride Chemical Name: 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide

Chemical Name: 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide

ζ-Stat can reduce melanoma cell lines proliferation and induce apoptosis

and its in vitro activity is altered in the presence of serum or albumin

CCT251545 potently inhibits WNT pathway activity in COLO205-F1756 clone 4 (an APC -mutant human colorectal cancer cell line engineered to express a modified luciferase-based WNT reporter construct) with an IC50 of 0

Isosilybin A - CAS# 142796-21-2 inib Hydrochloride Chemical Name: 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamideIsosilybin A, a flavonolignan isolated from silymarin, has anti prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt NF B androgen receptor (AR) axis. Product information CAS Number: 142796 21 2 Molecular Weight: 482. 44 Formula: C25H22O10 Chemical Name: (2R, 3R) 3, 5, 7 trihydroxy 2 [(2R, 3R) 2 (4 hydroxy 3