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leaded to complete and sustained regression of SMARCB1 mutant MRT xenografts (SCID mice bearing s
Beresford A
InChi: InChI=1S/C11H15N2O4PS/c1-6(2)5-8-10(13-11(12)19-8)7-3-4-9(17-7)18(14
25 to 20 μM
H-151 286638 free base leaded to complete and sustainedH 151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H 151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H 151 can be used for the research of autoinflammatory disease. Product information CAS Number: 941987 60 6 Molecular Weight: 279. 34 Formula: C17H17N3O Chemical Name: 1 (4 ethylphenyl) 3 (1H indol 3 yl)urea Smiles: