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SANT-1 ssium salt is structurally related to MGCD-265

SKU: 78472670610

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Description

is structurally related to MGCD-265 (Glesatinib)

PBTZ-169 has improved potency

CAS Number: 51549-30-5

The EC50 of Hymeglusin in K562 cells is 4

SANT-1 ssium salt is structurally related to MGCD-265SANT 1, a potent Smo antagonist, inhibits Hedgehog signaling. SANT 1 shows IC50s of 20 nM and 30 nM in Shh LIGHT2 and SmoA1 LIGHT2 assay, respectively. Product information CAS Number: 304909 07 7 Molecular Weight: 373. 49 Formula: C23H27N5 Chemical Name: N (4 benzylpiperazin 1 yl) 1 (3,5 dimethyl 1 phenyl 1H pyrazol 4 yl)methanimine Smiles: CC1=C(C=NN2CCN(CC3C=CC=CC=3)CC2)C(C)=NN1C1C=CC=CC=1 InChiKey: FOORCIAZMIWALX JJIBRWJFSA N InChi: InChI=1S

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