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Dolutegravir - CAS# 1051375-16-6 Catalog No.:M11383-2 CAS Number: 1225278-16-9

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CAS Number: 1225278-16-9

PIK-93 (250 nM) effectively abrogates the accumulation of CERT-PH domain and FL-Cer in Golgi

Y27632 inhibits the ROCK family of kinases 100 times more potently than other kinases including protein kinase C

43)38-11-8-18(9-12-38)34-28(41)26-23(16-32-36-26)35-27(40)25-21(30)13-17(29)14-22(25)31/h3-7

Dolutegravir - CAS# 1051375-16-6 Catalog No.:M11383-2 CAS Number: 1225278-16-9Dolutegravir, also known as GSK1349572, is a potent inhibitor of HIV integrase with an IC50 value of 2. 7 nM for HIV 1 integrase catalyzed strand transfer in vitro. 1 It inhibits HIV 1 viral replication (EC50 = 0. 51 nM) in peripheral blood mononuclear cells (PBMCs). Dolutegravir (DTG) is an antiretroviral medication used, together with other medication, to treat HIV AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV

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