LC-2, PROTACs for KRAS orvastatin (hemicalcium salt) Molecular Weight: 149

Name: LC-2, PROTACs for KRAS orvastatin (hemicalcium salt) Molecular Weight: 149
Brand: domainedesaintmeen.fr
SKU: 81501606881
Price: 495.00 USD
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SKU: 81501606881

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Description

Molecular Weight: 149

Formula: C44H72N6O11

Compared with the control

827319-43-7

LC-2, PROTACs for KRAS orvastatin (hemicalcium salt) Molecular Weight: 149LC 2 is the first PROTAC capable of degrading endogenous KRAS(G12C). It covalently binds KRASG12C with a MRTX849 warhead and recruits the E3 ligase VHL, inducing rapid and sustained KRASG12C degradation leading to suppression of MAPK signaling in both homozygous and heterozygous KRASG12C cell lines. Product information CAS Number: 2502156 03 6 Molecular Weight: 1132. 78 Formula: C59H71ClFN11O7S Chemical Name: (2S,4R) 1 [(2S) 2 (3 {3 [(2S) 2 ({[7 (8

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