Icilin is a synthetic super-agonist of the transient receptor potential M8 (TRPM8) ion channel
Jakobsen TH
Prexasertib dimesylate (4 nM
25(38)39-11-10-34)40-24(37)23-26(2
Lei-Dab7 TFA ximab Icilin is a synthetic super-agonistLei Dab7 TFA is a high affinity, selective KCa2. 2 (SK2) channel blocker (Kd=3. 8 nM). Lei Dab7 TFA exhibits >200 fold selectivity for KCa2. 2 over KCa2. 1, KCa2. 3, KCa3. 1, Kv and Kir2. 1. Lei Dab7 TFA increases theta burst responses and increases LTP in rat hippocampal slices in vitro. Product information Molecular Weight: 3508. 10 Formula: C143H239F3N46O41S6 Chemical Name: (3S, 6S, 9S, 12R, 15S, 18S, 21S, 27S, 30S, 36S, 39R, 42S, 48S) 48 (((S) 6