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R59022 (5 µM
Smiles: CC1C=CC(=CC=1)NC(=O)N1CCN(CC1)C1N=C(N)N=C2SC(=NC=12)C1=CN=CC=C1
and exposures are dose-dependent
Chemical Name: 4-[(4S)-4-(hydroxymethyl)-3-methyl-2
(2S, 3S)-E1R itrate R59022 (5 µM(2S,3S) E1R (Compound 2d) is an enantiomer of E1R. (2S,3S) E1R is a sigma 1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition memory disorders. Product information CAS Number: 1424832 57 4 Molecular Weight: 232. 28 Formula: C13H16N2O2 Chemical Name: 2 [(2S,3S) 2 methyl 5 oxo 3 phenylpyrrolidin 1 yl]acetamide Smiles: C[C@H]1[C@@H](CC(=O)N1CC(N)=O)C1C=CC=CC=1 InChiKey: ZTGRWYMPQCQTHD GXSJLCMTSA N InChi: InChI=1S
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