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3)21(17)19(27)13-23(18
Chemical Name: 5-(dimethylsulfamoyl)-N-(5-methyl-1
CG-806 exerts potent picomolar IC50 anti-proliferative activity against human AML cells and against Ba/F3 mouse AML cells with FLT3-ITD mutations (about 50 to 250-fold higher activity compared to quizartinib or gilteritinib)
CAS Number: 84625-61-6
Isorhynchophylline Catalog No.:M31156-C 3)21(17)19(27)13-23(18Isorhynchophylline (IRN), an alkaloid isolated from Uncaria rhynchophylla, possesses the effects of lowered blood pressure, vasodilatation and protection against ischemia induced neuronal damage. IC50 value: Target: In vitro: Isorhynchophylline concentration dependently inhibited the platelet derived growth factor (PDGF) BB induced proliferation of PASMCs. Fluorescence activated cell sorting analysis showed that isorhynchophylline caused G0 G1 phase
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