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PDE10A inhibitors have shown behavioral effects in rodent models that predict antipsychotic efficacy
Køhler L
At the 1 mg/kg dose CC-115 shows significant inhibition at 1 and 3 hours
Targeting ovarian cancer and chemoresistance through selective inhibition of sphingosine kinase-2 with ABC294640
T-26c 5207852 PDE10A inhibitors have shown behavioralT 26c is a highly potent and selective inhibitor of matrix metalloproteinase 13 (MMP 13) with IC50 of 6. 9 pM, more than 2600 fold selectivity over other related metalloenzymes. Product information CAS Number: 869296 13 9 Molecular Weight: 479. 51 Formula: C24H21N3O6S Chemical Name: 4 (((2 ((3 methoxybenzyl)carbamoyl) 4 oxo 3,4 dihydrothieno[2,3 d]pyrimidin 5 yl)methoxy)methyl)benzoic acid Smiles:
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