N-Desmethyl Droloxifene-d5 618epimostat dimethanesulfonate 4 nM for ACC1 (human)

4 nM for ACC1 (human)

The best scoring docking poses suggest that the binding site for EML 425 is an alternative pocket lying near the substrate lysine binding groove and close to the acetylation site

20-Hydroxyecdysone

Chemical Name: {4-[(1R)-2-amino-1-[(isoquinolin-6-yl)carbamoyl]ethyl]phenyl}methyl 2

N-Desmethyl Droloxifene-d5 618epimostat dimethanesulfonate 4 nM for ACC1 (human)Product information CAS Number: 1185241 63 7 Molecular Weight: 378. 52 Formula: C25H27NO2 Chemical Name: 3 [(1E) 1 {4 [2 (methylamino)ethoxy]phenyl} 2 phenyl(3,3,4,4,4 H)but 1 en 1 yl]phenol Smiles: [2H]C([2H])([2H])C([2H])([2H]) C(=C(\C1=CC(O)=CC=C1) C1C=CC(=CC=1)OCCNC) C1C=CC=CC=1 InChiKey: QPHNKIXIKDPNDI JFIRTRMYSA N InChi: InChI=1S C25H27NO2 c1 3 24(19 8 5 4 6 9 19)25(21 10 7 11 22(27)18 21)20 12 14 23(15 13 20)28 17 16 26 2 h4 15,18,26 27H,3,16