IQ 1 - CAS# 331001-62-8 60423 N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2

N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2

Smiles: C=CC(=O)N1C/C(=C/C2=CC(=C(F)C=C2)[N+]([O-])=O)/C(=O)/C(/CC1)=C\C1=CC(=C(F)C=C1)[N+]([O-])=O

InChiKey: ADNPLDHMAVUMIW-CUZNLEPHSA-N

oral gavage) induces a dose-dependent reduction in blood pressure in spontaneously hypertensive rat (SHR)

IQ 1 - CAS# 331001-62-8 60423 N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2IQ 1, CAS No. 331001 62 8, has many functions such as decreasing Wnt stimulated phosphorylation, maintaining the pluripotency of murine ESCs, preventing PP2A Nkd interaction and so on. IQ 1 maintains the pluripotency of murine ESCs in long term culture in a Wnt dependent manner. IQ 1 decreased Wnt stimulated phosphorylation of p300 at Ser 89.IQ 1 binds to serine threonine phosphatase PP2A and prevents PP2A Nkd interaction.The binding of IQ 1 to PR72