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Sofosbuvir 13CD3 (PSI-7977 13CD3) is the deuterium labeled Sofosbuvir
CAS Number: 356559-13-2
PubMed Central PMCID: PMC4697154
It is the first line treatment given its moderate side effects compared to nifurtimox
SKI-178 Size:10mg solid Sofosbuvir 13CD3 (PSI-7977 13CD3) isSKI 178 is a potent sphingosine kinase 1 (SphK1) and SphK2 inhibitor. SKI 178 is cytotoxic at IC50 concentrations ranging from 1. 8 to 0. 1 M in both drug sensitive and multi drug resistant cancer cell lines (i. e., MTR3, NCI ADR and HL60 VCR cells). SKI 178 induces apoptosis in a CDK1 dependent manner in human acute myeloid leukemia cell lines. Product information CAS Number: 1259484 97 3 Molecular Weight: 394. 42 Formula: C21H22N4O4 Chemical Name: