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mGlu5a and mGlu4a receptors respectively
Overstreet DH
and competitive antagonist of BET bromodomains to hijack the Cereblon E3 ubiquitin ligase complex
which does not require metabolism by dihydrofolate reductase
TOFA 8280 mGlu5a and mGlu4a receptors respectivelyTOFA (RMI14514; MDL14514) is an allosteric inhibitor of acetyl CoA carboxylase (ACCA ). Product information CAS Number: 54857 86 2 Molecular Weight: 324. 45 Formula: C19H32O4 Chemical Name: 5 (tetradecyloxy)furan 2 carboxylic acid Smiles: CCCCCCCCCCCCCCOC1=CC=C(O1)C(O)=O InChiKey: CZRCFAOMWRAFIC UHFFFAOYSA N InChi: InChI=1S C19H32O4 c1 2 3 4 5 6 7 8 9 10 11 12 13 16 22 18 15 14 17(23 18)19(20)21 h14 15H,2 13,16H2,1H3,(H,20,21) Technical Data