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Am580 treatment increased RARbeta and lowered the level of RARgamma
1186/s13054-017-1838-3
1401028-25-8 (free base
Formula: C17H14Cl2F2N2O3
IM-250 isantherin A Am580 treatment increased RARbeta andIM 250 not only reduces the duration of disease symptoms or time to healing but also prevents recurrent disease in guinea pigs. Treatment of recurrent infections reduces the frequency of recurrences and viral shedding, and, unlike nucleosidic drugs, IM 250 remains effective for a time after cessation of treatment. Hence, IM 250 has advantages over standard of care therapies and represents a promising therapeutic for chronic HSV infection, including
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