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EPZ004777 exhibits anti-proliferative activity against both MLL-rearranged and non-rearranged human leukemia cell lines
Smiles: CC(=O)N1CCN(CC1)C1C=CC(=CC=1)OC[C@H]1CO[C@@](CN2C=NC=C2)(O1)C1=CC=C(Cl)C=C1Cl
orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4
(±)11(12)-EET (5 μM
Apamin TFA Catalog No.:M15566-2 EPZ004777 exhibits anti-proliferative activity againstApamin TFA (Apamine TFA) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca2+ activated K+ (SK) channels and exhibits anti inflammatory and anti fibrotic activity. Product information Molecular Weight: 2141. 36 Formula: C81H132F3N31O26S4 Chemical Name: 3 [(1R, 4S, 7S, 13S, 16S, 19S, 22S, 25S, 28R, 31S, 34S, 37S, 40R, 47S, 50R) 50 amino 40 [[(2S) 5 amino 1 [[(2S) 5 amino 1 [[(2S) 1
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