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(S)-CFT7455 tinib bromide Linderalactone inhibits cancer growth by

SKU: 88874675743

4.5
USD100.00 USD124.00

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Description

Linderalactone inhibits cancer growth by modulating the expression of apoptosis-related proteins and inhibition of JAK/STAT signalling pathway

69 L/kg and area under the concentration-time curve (AUC0-24 h) of 48 h•μg/mL

Smiles: NC1=CC=CC=C1NC(=O)C1C=CC(CCCC(=O)NC2=CC=C(C=C2)[C@@H]2C[C@H]2N)=CC=1

4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one

(S)-CFT7455 tinib bromide Linderalactone inhibits cancer growth by(S) CFT7455 is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader. (S) CFT7455 is an anti cancer agent that binds with high affinity to the cereblon E3 ligase (Kd of 0. 9 nM)(WO2022032132A1; Compound 1). Product information CAS Number: 2504235 67 8 Molecular Weight: 469. 53 Formula: C28H27N3O4 Smiles: O=C1CC[C@@H](C(=O)N1)N1C2=CC=C(CC3=CC=C(CN4CCOCC4)C=C3)C3=CC=CC(=C23)C1=O InChiKey: MUKCJOOKCZSQNW DEOSSOPVSA N

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