Pay in 4 interest-free payments of $7.50 Learn more
Ships within 48 hours · Estimated delivery Aug 5 - Aug 10
InChiKey: WGIKEBHIKKWJLG-UHFFFAOYSA-N
1346546-69-7
respectively) and no activity against EGFR
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation
LY2835219 free base - CAS# 1231929-97-7 size:2mg solid InChiKey: WGIKEBHIKKWJLG-UHFFFAOYSA-NLY2835219 free base, CAS No. 1231929 97 7, is orally available cyclin dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. LY2835219 inhibits CDK4 and CDK6 with low nanomolar potency. LY2835219 specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation in early G1. Inhibition of Rb phosphorylation prevents CDK mediated