W-84 dibromide 17592 and Cathepsin B with Kis

and Cathepsin B with Kis of <20 nM

CC1C=C(C)C(=CC=1)SC1=CC=CC=C1N1CCNCC1

3-dihydro-1H-indol-2-yl]methoxy}-3-(tert-butylsulfanyl)-1-{[4-(5-methoxypyrimidin-2-yl)phenyl]methyl}-1H-indol-2-yl)-2

InChiKey: KAEGGIFPLJZUOZ-UHFFFAOYSA-N

W-84 dibromide 17592 and Cathepsin B with KisW 84 (dibromide) is a potent allosteric modulator of M2 cholinoceptors, which retards [3H]N methylscopolamine dissociation. W 84 dibromide can stabilize cholinergic antagonist receptor complexes. W 84 (dibromide) is a non competitive muscarinic acetylcholine receptors antagonist with allosteric effects. W 84 (dibromide) protects over additively against an organophosphate intoxication when applied in combination with atropine. Product information CAS