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InChi: InChI=1S/C20H31N3O/c24-20(22-19-9-5-2-6-10-19)23(15-17-7-3-1-4-8-17)16-18-11-13-21-14-12-18/h1
a dual specificity threonine/tyrosine kinase
InChiKey: ZVQCWVLBPYOZNC-XNCCLBLBSA-N
5-8 hours) results in a concentration-dependent reduction of ErbB2 receptor phosphorylation
Tankyrase-IN-2 Catalog No.:M14406-2 InChi: InChI=1S/C20H31N3O/c24-20(22-19-9-5-2-6-10-19)23(15-17-7-3-1-4-8-17)16-18-11-13-21-14-12-18/h1Tankyrase IN 2 (compound 5k) is a potent, selective, and orally active tankyrase inhibitor (IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectively). Tankyrase IN 2 has favorable physicochemical profile and pharmacokinetic properties modulating Wnt pathway activity in a colorectal xenograft model. Product information CAS Number: 1588870 36 3 Molecular Weight: 316. 30 Formula: C17H14F2N2O2 Chemical Name: 6,8 difluoro 2 [4 (2
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