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4-dichlorophenyl)-6-oxopiperidin-3-yl]ethyl}azetidin-3-yl)piperazine-1-sulfonamide
a first-in-class pan-NADPH oxidase (Nox) inhibitor
A dose-dependent reduction in the NRF2 transcriptional activity is observed and the maximum inhibitory concentration is 5 μM by ML385
CAS Number: 659730-32-2
BMS-654457 Catalog No.:M20404-C 4-dichlorophenyl)-6-oxopiperidin-3-yl]ethyl}azetidin-3-yl)piperazine-1-sulfonamideBMS 654457 is a small molecule, reversible inhibitor of factor XIa (FXIa), binding with human and rabbit FXIa with Kis of 0. 2 and 0. 42 nM, respectively. Product information CAS Number: 1004551 41 0 Molecular Weight: 603. 71 Formula: C36H37N5O4 Chemical Name: 3' [(2S,4R) 6 carbamimidoyl 4 methyl 4 phenyl 1,2,3,4 tetrahydroquinolin 2 yl] 4 carbamoyl 5' (3 methylbutanamido) [1,1' biphenyl] 2 carboxylic acid Smiles:
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