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PF-4693627 shows high activity in lipopolysaccharide (LPS) stimulated human whole blood (HWB) cell assay (IC50=109 nM)
Chemical Name: 4-[5-(²H₃)methyl-3-phenyl-1
the 50 mg/kg dose was decreased to 30 mg/kg
only binding at the glycine (57%)
Direct Black 38 Catalog No.:M31253-C PF-4693627 shows high activity inDirect Black 38 (Chlorazol Black E) is an azo dye. Direct Black 38 induces unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats in vivo. Product information CAS Number: 1937 37 7 Molecular Weight: 781. 73 Formula: C34H25N9Na2O7S2 Chemical Name: disodium 4 amino 3 (2 {4' [2 (2,4 diaminophenyl)diazen 1 yl] [1,1' biphenyl] 4 yl}diazen 1 yl) 5 hydroxy 6 (2 phenyldiazen 1 yl)naphthalene 2,7 disulfonate Smiles: [Na+].[Na+].