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PQR-309 - CAS# 1225037-39-7 0216 2001 Mar 6

SKU: 94169140259

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Description

2001 Mar 6

2015 Jan 15

CID 25010775

WO2015092740A1

PQR-309 - CAS# 1225037-39-7 0216 2001 Mar 6PQR 309, CAS No. 1225037 39 7, is an orally bioavailable pan inhibitor of phosphoinositide 3 kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity. PI3K mTOR kinase inhibitor PQR 309 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K mTOR. Activation of

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