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SB-423557 tinal-d5 [Epub ahead of print] PubMed

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Description

[Epub ahead of print] PubMed PMID: 25064435

Formula: C22H27ClN6O

27-nonaoxanonacosan-1-ol

InChi: InChI=1S/C21H25N5O2/c1-13-10-26(11-14(2)27-13)19-9-18(22-12-23-19)20-16-8-15(28-21(3)6-7-21)4-5-17(16)24-25-20/h4-5

SB-423557 tinal-d5 [Epub ahead of print] PubMedSB 423557 is an orally active calcium sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB 423562 (IC50=73 nM). SB 423557 is well tolerated in human and increases plasma concentrations of exogenous parathyroid hormone (PTH) and stimulates bone formation. Product information CAS Number: 351490 26 1 Molecular Weight: 464. 60 Formula: C28H36N2O4 Chemical Name: ethyl 3 [4 cyano 3 (3 {[1 (2,3 dihydro 1H inden 2 yl) 2 methylpropan 2 yl]amino} 2

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