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MHY1485 serves as a novel inhibitor of autophagy with an mTOR activating effect
is a highly potent and selective Aurora A inhibitor with an IC50 of 1
Oral Aticaprant (CERC-501) administration selectively and potently occupies central kappa opioid receptors (ED50=0
6) with no measurable affinity for hPPARα or hPPARγ (pIC50 < 5) in our standard in vitro ligand displacement assay
LY-303511 - CAS# 154447-38-8 Catalog No.:M6665-10 MHY1485 serves as a novelLY 303511, CAS No. 154447 38 8, also known as NV 128 and EM 101, is a potent mTOR inhibitor. LY 303511 enhances TRAIL sensitivity of SHEP 1 neuroblastoma cells via hydrogen peroxide mediated mitogen activated protein kinase activation and up regulation of death receptors. LY 303511 amplifies TRAIL induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization. LY 303511 acts via
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