N-(3-hydroxyphenyl)-Arachidonoyl amide isqualic acid 3-d]pyrano[4'

3-d]pyrano[4'

Hesperin is a bioactive ingredient present in Japanese horseradish (wasabi) and has been shown to be an Nrf2 activator

Formula: C25H23ClN2O3S2

2% cholesterol diet and dosed with 36 nmoles/kg/day KAT681 or a respective placebo control for 4 weeks

N-(3-hydroxyphenyl)-Arachidonoyl amide isqualic acid 3-d]pyrano[4'IC50: 2 M N (3 hydroxyphenyl) Arachidonoyl amide, also known as 3 HPAA, is an analog of AM404 (N (4 hydroxyphenyl) arachidonoyl amide), a selective inhibitor of carrier mediated transport of arachidonoyl ethanolamide. 3 HPAA, metabolized by both cyclooxygenase (COX) 1 and COX 2, is an irreversible and selective inhibitor of COX 2 with an IC50 value of 2 M. 3 HPAA can be efficiently oxygenated to prostaglandin and hydroxyeicosatetraenoate products by