Solasodine rolithin B Pimecrolimus blocks T-lymphocyte activation pathway

Pimecrolimus blocks T-lymphocyte activation pathway by inhibiting calcineurin function

CCR5 and CXCR4

In 3-day MTS cell proliferation assays

CN111320630A

Solasodine rolithin B Pimecrolimus blocks T-lymphocyte activation pathwaySolasodine (Purapuridine, Solancarpidine, Solasodin, Salasodine, Salasdine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine reduces the mRNA level of matrix metalloproteinase 2 (MMP 2), MMP 9 and extracellular inducer of matrix metalloproteinase (EMMPRIN), but increases the expression of reversion inducing cysteine rich protein with kazal motifs (RECK). Solasodine downregulates oncogenic microRNA 21