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Y27632 (5 and 10 mg/kg) significantly prolongs the onset time of clonic convulsions when compare with saline group
Current Topics in Medicinal Chemistry (Sharjah
72C:243-253
1) channels (EC50s range from 0
BMS-265246 175 Y27632 (5 and 10 mg/kg)BMS 265246 is a potent CDK1 CDK2 selective inhibitor [(CDK1 cycB IC(50)=6 nM, CDK2 cycE IC(50)=9 nM)]. Product information CAS Number: 582315 72 8 Molecular Weight: 345. 34 Formula: C18H17F2N3O2 Chemical Name: 4 butoxy 5 (2,6 difluoro 4 methylbenzoyl) 2H pyrazolo[3,4 b]pyridine Smiles: CC1C=C(F)C(=C(F)C=1)C(=O)C1C=NC2=NNC=C2C=1OCCCC InChiKey: SCFMWQIQBVZOQR UHFFFAOYSA N InChi: InChI=1S C18H17F2N3O2 c1 3 4 5 25 17 11(8 21 18 12(17)9 22 23 18)16(24)15
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