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IRE1α oligomerizes
together with the realization that KYNA concentrations in the mammalian brain are in the sub-micromolar range
InChi: InChI=1S/C51H77N7O9S/c1-12-34(6)46(56(9)51(65)44(32(2)3)54-49(64)45(33(4)5)55(8)40(59)23-17-14-18-27-58-41(60)24-25-42(58)61)39(66-10)31-43(62)57-28-19-22-38(57)47(67-11)35(7)48(63)53-37(50-52-26-29-68-50)30-36-20-15-13-16-21-36/h13
which are comparable to values obtained in T-cell lines
ILK-IN-2 3782 IRE1α oligomerizesILK IN 2 (OSU T315 analog) is a ILK inhibitor. Product information CAS Number: 1333146 24 9 Molecular Weight: 533. 59 Formula: C30H30F3N5O Chemical Name: N methyl 3 {1 [4 (piperazin 1 yl)phenyl] 3 [4' (trifluoromethyl) [1,1' biphenyl] 4 yl] 1H pyrazol 5 yl}propanamide Smiles: CNC(=O)CCC1C=C(C2C=CC(=CC=2)C2C=CC(=CC=2)C(F)(F)F)N(N=1)C1C=CC(=CC=1)N1CCNCC1 InChiKey: GHBUPSVATJKTRR UHFFFAOYSA N InChi: InChI=1S C30H30F3N5O c1 34 29(39)15 10 25 20 28(38(36
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