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peripheral blood and bone marrow specimens from patients with leukemia and mitogenically (phytohemagglutinin) or antigenically (mixed lymphocyte culture) stimulated human peripheral blood cultures
2014 Feb 28
Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs
11a-trihydrogenio-11-hydroxy-1-[(2S
AKT-IN-6 Catalog No.:M32827-C peripheral blood and bone marrowAKT IN 6 (Example 13) is a potent Akt inhibitor. AKT IN 6 inhibits Akt1, Akt2 and Akt3 with IC50s < 500nM, respectively. (patent WO2013056015A1). Product information CAS Number: 1430056 54 4 Molecular Weight: 389. 43 Formula: C22H20FN5O Chemical Name: 5 {2 [(2S) 1 amino 3 (3 fluorophenyl)propan 2 yl] 1 oxo 2,3 dihydro 1H isoindol 5 yl} 1 methyl 1H pyrazole 4 carbonitrile Smiles: CN1N=CC(C#N)=C1C1=CC2CN([C@H](CN)CC3=CC(F)=CC=C3)C(=O)C=2C=C1 InChiKey:
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