Play Sheriff of Nottingham with the likes of A Whole New World, which forces players to discard their entire hand to draw back up to seven cards and thats potentially a huge chunk of damage in a single blow - especially as Lorcana has no hand-limit
Much like Aladdin, Heroic Outlaw, Robin, Champion of Sherwood will net you a tasty two lore whenever he banishes an opposing character in a challenge - a shame his steel identity means he wont be forcing your opponent to lose lore as well like his predecessor
As another example, if my opening hand has a one-drop, a two-drop, a three-drop and four different four-drops, then I will usually bottom the worst three four-drops in the hope of drawing into a powerful five or six-drop, while keeping the cards that will ensure a perfect 1-2-3-4 curve-out
Locations tend to have a lot of Willpower, so including a powerhouse like And Then Along Came Zeus makes it easy to bring down a location in a single turn