Wistfulness, Vibrance, Emptiness, Deceit, and Catharsis change what they do based on the colors you use to cast them, which makes every decision feel meaningful
(Look at the top X cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.) Once Lydia Frye has been blocked, increasing the blocking creature's power to 3 or greater won't cause Lydia Frye to become unblocked
(Choose any number of permanents and/or players, then give each another counter of each kind already there.) , , Sacrifice another artifact: Proliferate
Along the way, there are plenty of obvious winners: cards that become pro tournament staples, others that skyrocket in price due to rarity and usefulness, and everything in between