I asked the other players, who were tapped out if any of them could stop it, they said no, and I asked if they could if they had mana
"When you're talking to us and then Final Fantasy comes along and says 'Why don't you make a FF one?' then the Brandon Sandersons of the world, they're like 'We'll talk to you later'," the author explained
Whenever Mishra, Lost to Phyrexia attacks or enters the battlefield, you get to choose three from having an opponent discard two cards, dealing three damage to something, destroying an artifact or planeswalker, giving your creature menace and trample, giving enemy creatures -1/-4, or creating two Powerstone tokens
It seems like it just might be fast enough (of course those plays outlined above were of the optimal sort) that it may not need any Kraken Hatchlings, Isleback Spawns, counterspells or the like to help it get there, though you may never end up playing Jace's Ultimate because he'll probably take a lot of beats, but hey, that's almost the same as gaining life, and anyhow, once he's dead, you could very well have drawn into another one, so that works out too