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Formula: C20H29N5O3
ClH/c1-19-13-15-8-3-5-11-17(15)20-18-12-6-9-14-7-2-4-10-16(14)18
Methysticin triggers the most profound inducing effect on CYP1A1
C23H16O6/c59-27-13-12-22-46-52(69)64-47(30-38-23-25-42(26-24-38)76-36-39-16-6-2-7-17-39)53(70)66-49(31-37-14-4-1-5-15-37)57(74)68-35-43(77-58(75)61-29-28-60)33-50(68)55(72)67-51(40-18-8-3-9-19-40)56(73)65-48(54(71)63-46)32-41-34-62-45-21-11-10-20-44(41)45
Lumateperone tosylate y-1-Methoxyaporphine Formula: C20H29N5O3Lumateperone tosylate (ITI 007 tosylate) is a 5 HT2A receptor antagonist (Ki = 0. 54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM). IC50 value: 0. 54 nM (Ki, for 5 HT2A receptor )Target: 5 HT2A receptorLumateperone also possesses affinity for the D1 receptor (Ki = 52 nM) and weak affinity for the 1A and 1B adrenergic receptors (Ki = 173 nM at 1) and D4
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